Lyreleaf sage is an herbaceous perennial in the Lamiaceae (mint) family and native to the eastern and central United States. It may grow 1 to 2 feet tall, with leaves that originate at the base of the stem. Each basal leaf is lobed like a lyre, hence the species name, and lavender flowers occur in rings around the stem from mid-spring to early summer, attracting butterflies. The name Salvia is derived from the Latin term salve o, which means ‘be well’ and refers to the plant's medicinal properties.

Plant in average, medium-moist, well-drained soil in full sun to partial shade. It tolerates heat and humidity, as well as drought once established. Lyreleaf sage is moderately resistant to browsing by deer. Propagate by collecting seeds before seed capsules fully dry out or by root division. It reseeds easily in loose, sandy soil.

Use this sage in a meadow, naturalized area, or woodland. Its dense form, short height, and tolerance for mowing make it an excellent lawn alternative. Plant it in a butterfly, drought tolerant, native, or pollinator garden. Because it tolerates occasional flooding and wet soil, it makes a good addition to a rain garden. American goldfinches will visit them for the seeds.

Host plant for several species of Lepidoptera larvae, including Wavy-lined Emerald moths and Hermit Sphinx moths .